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1

Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment

Chikara, Shireen, Nagaprashantha, Lokesh Dalasanur, Singhal, Jyotsana, Horne, David, Awasthi, Sanjay, Singhal, Sharad S.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

2

The sensors and regulators of cell–matrix surveillance in anoikis resistance of tumors

Lokesh Dalasanur Nagaprashantha, Rit Vatsyayan, Poorna Chandra Rao Lelsani, Sanjay Awasthi, Sharad S. Singhal

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

3

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer

Lokesh Dalasanur Nagaprashantha, Rit Vatsyayan, Jyotsana Singhal, Spence Fast, Rhonda Roby, Sanjay Awasthi, Sharad S. Singhal

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

4

2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76

Singhal, Jyotsana, Chikara, Shireen, Horne, David, Salgia, Ravi, Awasthi, Sanjay, Singhal, Sharad S

Journal:

Molecular Carcinogenesis

Year:

2018

File:

PDF, 1.31 MB

2018

5

RLIP: An existential requirement for breast carcinogenesis

Singhal, Sharad S., Salgia, Ravi, Singhal, Sulabh, Horne, David, Awasthi, Sanjay

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2019

Language:

english

File:

PDF, 684 KB

english, 2019

6

Modulation of doxorubicin cytotoxicity by ethacrynic acid

Sanjay Awasthi, Sharad S. Singhal, Nong-gao He, Meena Chaubey, Piotr Zimniak, Sanjay K. Srivastava, Shivendra V. Singh, Yogesh C. Awasthi

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 827 KB

english, 1996

7

Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): A novel link between G-protein and tyrosine kinase signaling and drug resistance

Sanjay Awasthi, Sharad S. Singhal, Rajendra Sharma, Piotr Zimniak, Yogesh C. Awasthi

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 1.30 MB

english, 2003

8

RLIP76 (RALBP1)-mediated transport of leukotriene C4 (LTC4) in cancer cells: Implications in drug resistance

Rajendra Sharma, Sharad S. Singhal, Dilki Wickramarachchi, Yogesh C. Awasthi, Sanjay Awasthi

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 258 KB

english, 2004

9

Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer

Sharad S. Singhal, Archana Sehrawat, Mukesh Sahu, Preeti Singhal, Rit Vatsyayan, Poorna Chandra Rao Lelsani, Sushma Yadav, Sanjay Awasthi

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 613 KB

english, 2010

10

Glutathione S-transferase-catalyzed conjugation of 9,10-epoxystearic acid with glutathione

Rajendra Sharma, Sanjiv Gupta, Sharad S. Singhal, G. A. S. Ansari, Dr. Yogesh C. Awasthi

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1991

Language:

english

File:

PDF, 626 KB

english, 1991

11

Human glutathione S-transferases

Yogesh C. Awasthi, Rashmi Sharma, Sharad S. Singhal

Journal:

International Journal of Biochemistry

Year:

1994

Language:

english

File:

PDF, 1.61 MB

english, 1994

12

Purification and characterization of glutathione S-transferase from sugarcane leaves

Sharad S. Singhal, Narendra K. Tiwari, Hassan Ahmad, Satish K. Srivastava, Yogesh C. Awasthi

Journal:

Year:

1991

Language:

english

File:

PDF, 705 KB

english, 1991

13

RLIP76 in Defense of Radiation Poisoning

Jyotsana Singhal, Sharad S. Singhal, Sushma Yadav, Sumihiro Suzuki, Molly M. Warnke, Adly Yacoub, Paul Dent, Sejong Bae, Rajendra Sharma, Yogesh C. Awasthi, Daniel W. Armstrong, Sanjay Awasthi

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

14

The determination of glutathione-4-hydroxynonenal (GSHNE),E-4-hydroxynonenal (HNE), andE-1-hydroxynon-2-en-4-one (HNO) in mouse liver tissue by LC-ESI-MS

Molly M. Warnke, Eranda Wanigasekara, Sharad S. Singhal, Jyotsana Singhal, Sanjay Awasthi, Daniel W. Armstrong

Journal:

Analytical and Bioanalytical Chemistry

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

15

Linking stress-signaling, glutathione metabolism, signaling pathways and xenobiotic transporters

Sushma Yadav, Ewa Zajac, Sharad S. Singhal, Sanjay Awasthi

Journal:

Cancer and Metastasis Reviews

Year:

2007

Language:

english

File:

PDF, 363 KB

english, 2007

16

Novel Anti-cancer Compounds for Developing Combinatorial Therapies to Target Anoikis-Resistant Tumors

Lokesh Nagaprashantha, Neha Vartak, Sangeeta Awasthi, Sanjay Awasthi, Sharad S. Singhal

Journal:

Pharmaceutical Research

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

17

RLIP76 in AED drug resistance

Damir Janigro, Sanjay Awasthi, Yogesh C. Awasthi, Rajendra Sharma, Sushma Yadav, Sharad S. Singhal, Kerri Hallene

Journal:

Year:

2007

Language:

english

File:

PDF, 96 KB

english, 2007

18

Novel Function of Human RLIP76: ATP-Dependent Transport of Glutathione Conjugates and Doxorubicin†

Awasthi, Sanjay, Cheng, Jizhong, Singhal, Sharad S., Saini, Manjit K., Pandya, Utpal, Pikula, Slawomir, Bandorowicz-Pikula, Joanna, Singh, Shivendra V., Zimniak, Piotr, Awasthi, Yogesh C.

Journal:

Year:

2000

Language:

english

File:

PDF, 219 KB

english, 2000

19

Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma

Rit Vatsyayan, Jyotsana Singhal, Lokesh Dalasanur Nagaprashantha, Sanjay Awasthi, Sharad S. Singhal

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 580 KB

english, 2012

20

Rabbit Aorta GlutathioneS-Transferases and Their Role in Bioactivation of Trinitroglycerin

Sharad S. Singhal, John T. Piper, Sanjay K. Srivastava, Meena Chaubey, Joanna Bandorowicz-Pikula, Sanjay Awasthi, Yogesh C. Awasthi

Journal:

Toxicology and Applied Pharmacology

Year:

1996

Language:

english

File:

PDF, 175 KB

english, 1996

21

GlutathioneS-Transferases of Rabbit Lung Macrophages

Robert J. Morrison, Sharad S. Singhal, Akhil Bidani, Thomas A. Heming, Sanjay Awasthi

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 270 KB

english, 1998

22

The Role of GlutathioneS-Transferases as a Defense against Reactive Electrophiles in the Blood Vessel Wall

Nong Gao He, Sanjay Awasthi, Sharad S. Singhal, Margaret B. Trent, Paul J. Boor

Journal:

Toxicology and Applied Pharmacology

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

23

ATP-Dependent Colchicine Transport by Human Erythrocyte Glutathione Conjugate Transporter

Sanjay Awasthi, Sharad S. Singhal, Utpal Pandya, Sanjiv Gopal, Piotr Zimniak, Shivendra V. Singh, Yogesh C. Awasthi

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 145 KB

english, 1999

24

Role of Glutathione S-transferase 8-8 in Allylamine Resistance of Vascular Smooth Muscle Cells in Vitro

Nonggao He, Sharad S Singhal, Sanjay Awasthi, Tiejun Zhao, Paul J Boor

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999

25

Gender related differences in the expression and characteristics of glutathione S-transferases of human colon

Sharad S. Singhal, Manju Saxena, Sanjay Awasthi, Hassan Ahmad, Rashmi Sharma, Yogesh C. Awasthi

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1992

Language:

english

File:

PDF, 806 KB

english, 1992

26

Purification and characterization of glutathione S-transferases from rat pancreas

Sharad S. Singhal, Sanjiv Gupta, Manju Saxena, Rajendra Sharma, Hassan Ahmad, G.A.S. Ansari, Yogesh C. Awasthi

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

Language:

english

File:

PDF, 852 KB

english, 1991

27

Glutathione S-transferases of human skin: qualitative and quantitative differences in men and women

Sharad S. Singhal, Manju Saxena, Sanjay Awasthi, Hasan Mukhtar, Syed I.A. Zaidi, Hassan Ahmad, Yogesh C. Awasthi

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 755 KB

english, 1993

28

Characterization of two novel subunits of the α-class glutathione S-transferases of human liver

Hassan Ahmad, Sharad S. Singhal, Manju Saxena, Yogesh C. Awasthi

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1993

Language:

english

File:

PDF, 446 KB

english, 1993

29

A novel glutathione S-transferase isozyme similar to GST 8-8 of rat and mGSTA4-4 (GST 5.7) of mouse is selectively expressed in human tissues

Sharad S. Singhal, Piotr Zimniak, Rashmi Sharma, Sanjay K. Srivastava, Sanjay Awasthi, Yogesh C. Awasthi

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1994

Language:

english

File:

PDF, 992 KB

english, 1994

30

Comparative studies on the effect of butylated hydroxyanisole on glutathione and glutathione S-transferases in the tissues of male and female CD-1 mice

Rashmi Sharma, Hassan Ahmad, Sharad S. Singhal, Manju Saxena, Sanjay K. Srivastava, Yogesh C. Awasthi

Journal:

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology

Year:

1993

Language:

english

File:

PDF, 802 KB

english, 1993

31

Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin

Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Ewa Zajac, Yogesh C. Awasthi, Sanjay Awasthi

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

32

Regression of prostate cancer xenografts by RLIP76 depletion

Sharad S. Singhal, Cherice Roth, Kathryn Leake, Jyotsana Singhal, Sushma Yadav, Sanjay Awasthi

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 612 KB

english, 2009

33

hSET1: A novel approach for colon cancer therapy

Sushma Yadav, Jyotsana Singhal, Sharad S. Singhal, Sanjay Awasthi

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 337 KB

english, 2009

34

RLIP76: A versatile transporter and an emerging target for cancer therapy

Rit Vatsyayan, Poorna Chandra Rao Lelsani, Sanjay Awasthi, Sharad S. Singhal

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 206 KB

english, 2010

35

Diminished drug transport and augmented radiation sensitivity caused by loss of RLIP76

Sharad S. Singhal, Sushma Yadav, Jyotsana Singhal, Mukesh Sahu, Archana Sehrawat, Sanjay Awasthi

Journal:

Year:

2008

Language:

english

File:

PDF, 421 KB

english, 2008

36

Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death

Yogesh C. Awasthi, Rajendra Sharma, Abha Sharma, Sushma Yadav, Sharad S. Singhal, Pankaj Chaudhary, Sanjay Awasthi

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 325 KB

english, 2008

37

Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase μ

Julie K Horton, Gargi Roy, John T Piper, Bennett Van Houten, Yogesh C Awasthi, Sankar Mitra, Moulay A Alaoui-Jamali, Istvan Boldogh, Sharad S Singhal

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 386 KB

english, 1999

38

Curcumin–glutathione interactions and the role of human glutathione S-transferase P1-1

Sanjay Awasthi, Utpal Pandya, Sharad S. Singhal, James T. Lin, Varatharasa Thiviyanathan, William E. Seifert Jr., Yogesh C. Awasthi, G.A.S. Ansari

Journal:

Chemico-Biological Interactions

Year:

2000

Language:

english

File:

PDF, 393 KB

english, 2000

39

Naturally Occurring Human Glutathione S-transferase GSTP1-1 Isoforms with Isoleucine and Valine in Position 104 Differ in Enzymic Properties

Piotr Zimniak, Bindu Nanduri, Sławomir Pikuła, Joanna Bandorowicz-Pikuła, Sharad S. Singhal, Sanjay K. Srivastava, Sanjay Awasthi, Yogesh C. Awasthi

Journal:

Year:

1994

Language:

english

File:

PDF, 931 KB

english, 1994

40

ATP-Dependent Human Erythrocyte Glutathione-Conjugate Transporter. I. Purification, Photoaffinity Labeling, and Kinetic Characteristics of ATPase Activity†

Awasthi, Sanjay, Singhal, Sharad S., Srivastava, Sanjay K., Torman, Robert T., Zimniak, Piotr, Bandorowicz-Pikula, Joanna, Singh, Shivendra V., Piper, John T., Awasthi, Yogesh C., Pikula, Slawomir

Journal:

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

41

Transfection of a 4-Hydroxynonenal Metabolizing GlutathioneS-Transferase Isozyme, Mouse GSTA4-4, Confers Doxorubicin Resistance to Chinese Hamster Ovary Cells

Nong-Gao He, Sharad S. Singhal, Sanjay K. Srivastava, Piotr Zimniak, Yogesh C. Awasthi, Sanjay Awasthi

Journal:

Archives of Biochemistry and Biophysics

Year:

1996

Language:

english

File:

PDF, 141 KB

english, 1996

42

Differential Catalytic Efficiency of Allelic Variants of Human GlutathioneS-Transferase Pi in Catalyzing the Glutathione Conjugation of Thiotepa

Sanjay K. Srivastava, Sharad S. Singhal, Xun Hu, Yogesh C. Awasthi, Piotr Zimniak, Shivendra V. Singh

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 72 KB

english, 1999

43

The Role of Human Glutathione S-Transferases hGSTA1-1 and hGSTA2-2 in Protection against Oxidative Stress

Tiejun Zhao, Sharad S. Singhal, John T. Piper, Jizhong Cheng, Utpal Pandya, Julianna Clark-Wronski, Sanjay Awasthi, Yogesh C. Awasthi

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

44

Effects of mGST A4 Transfection on 4-Hydroxynonenal-Mediated Apoptosis and Differentiation of K562 Human Erythroleukemia Cells

Ji-Zhong Cheng, Sharad S. Singhal, Manjit Saini, Jyotsana Singhal, John T. Piper, F.J.G.M. Van Kuijk, Piotr Zimniak, Yogesh C. Awasthi, Sanjay Awasthi

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 259 KB

english, 1999

45

Transfection of mGSTA4 in HL-60 Cells Protects against 4-Hydroxynonenal-Induced Apoptosis by Inhibiting JNK-Mediated Signaling

Ji-Zhong Cheng, Sharad S. Singhal, Abha Sharma, Manjit Saini, Yusong Yang, Sanjay Awasthi, Piotr Zimniak, Yogesh C. Awasthi

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 398 KB

english, 2001

46

RLIP76 Is the Major ATP-Dependent Transporter of Glutathione-Conjugates and Doxorubicin in Human Erythrocytes

Rajendra Sharma, Sharad S. Singhal, Jizhong Cheng, Yusong Yang, Abha Sharma, Piotr Zimniak, Sanjay Awasthi, Yogesh C. Awasthi

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 361 KB

english, 2001

47

Activity of Allelic Variants of Pi Class Human Glutathione S-Transferase Toward Chlorambucil

Utpal Pandya, Sanjay K. Srivastava, Sharad S. Singhal, Ajai Pal, Sanjay Awasthi, Piotr Zimniak, Yogesh C. Awasthi, Shivendra V. Singh

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 62 KB

english, 2000

48

Two Distinct 4-Hydroxynonenal Metabolizing Glutathione S-Transferase Isozymes Are Differentially Expressed in Human Tissues

Ji-Zhong Cheng, Yusong Yang, Sharda P. Singh, Sharad S. Singhal, Sanjay Awasthi, Su-Shu Pan, Shivendra V. Singh, Piotr Zimniak, Yogesh C. Awasthi

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 145 KB

english, 2001

49

A Group of Novel Glutathione S-transferase Isozymes Showing High Activity Towards 4-hydroxy-2-nonenal are Present in Bovine Ocular Tissues

Sanjay K. Srivastava, Sharad S. Singhal, Krishna K. Bajpai, Meena Chaubey, Naseem H. Ansari, Yogesh C. Awasthi

Journal:

Experimental Eye Research

Year:

1994

File:

PDF, 579 KB

1994

50

A Glutathione S-transferases Isozyme (bGST 5.8) Involved in the Metabolism of 4-Hydroxy-2-trans-nonenal is Localized in Bovine Lens Epithelium

SANJAY K. SRIVASTAVA, SHARAD S. SINGHAL, SANJAY AWASTHI, SLAWOMIR PIKULA, NASEEM H. ANSARI, YOGESH C. AWASTHI

Journal:

Experimental Eye Research

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996